ABSTRACT

Primary central nervous system (CNS) lymphoma is a rare form of extranodal non-Hodgkin’s lymphoma. It constitutes 1% of all intracranial tumours. The most common histologic subtype is high grade diffuse large B cell lymphoma. It commonly presents with neurological signs and ocular symptoms. The diagnosis requires histopathologic confirmation of lymphoma and exclusion of the lymphoma involvement at sites other than the CNS. Its treatment usually includes a combination of chemotherapy and radiotherapy. Here, we report a patient who was diagnosed with primary CNS lymphoma at our clinic. The patient presented with neurologic and ocular symptoms. A cerebral mass was identified on MRI. A histological diagnosis of lymphoma was made after surgical excision of the cerebral mass. No lymphoma involvement was found on PET scan and bone marrow biopsy. Thus, the patient was diagnosed with primary extranodal CNS lymphoma.

Keywords: Lymphoma, large B-Cell, diffuse, brain neoplasms, blind ness