A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region
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Original Article
P: 118-120
December 2016

A Comparison of Fine Needle Aspiration Biopsy and Excisional Biopsy Results in the Diagnosis of Lymphoma Confined to the Head and Neck Region

İstanbul Med J 2016;17(4):118-120
1. Clinic of Otorhinolaryngology, İstanbul Training and Research Hospital, İstanbul, Türkiye
2. Clinic of Otorhinolaryngology, Lüleburgaz State Hospital, Kırklareli, Türkiye
3. Clinic of Otorhinolaryngology, Bozyaka Training and Research Hospital, İzmir, Türkiye
4. Clinic of Radiology, İstanbul Training and Research Hospital, İstanbul, Türkiye
5. Clinic of Pathology, İstanbul Training and Research Hospital, İstanbul, Türkiye
No information available.
No information available
Received Date: 24.06.2016
Accepted Date: 18.08.2016
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ABSTRACT

Objective:

To compare fine needle aspiration biopsy (FNAB) and excisional biopsy results in the diagnosis of head and neck lymphomas and to evaluate the effectiveness of FNAB.

Methods:

The medical files of 52 patients diagnosed with lymphoma in our clinic between September 2011 and January 2015 were retrospectively examined. Demographic characteristics, presenting complaints, hematologic parameters, fine needle aspiration biopsy (FNAB) results, and excisional biopsy results of the patients were recorded. The patients were divided into 4 groups based on their FNAB cytology results: i) malignant cytology, ii) suspicious for lymphoid neoplasia, iii) mixed lymphoid cell population, and iv) non-diagnostic cytology. FNAB was performed under ultrasound guidance.

Results:

The average age within our series, which consisted of 37 male and 15 female patients, was 46.37 (range 8–82 years). Neck mass was the presenting symptom in 30 patients (57.6%), while it was detected during examination of other symptoms in 22 patients (42.3%). Fever was not observed in any of the patients, whereas weight loss was present in 12 patients (23%), fatigue in 5 patients (9.6%), and night sweats in 5 patients (9.6%). Following excisional biopsy, Hodgkin lymphoma was diagnosed in 28 patients and non-Hodgkin lymphoma was diagnosed in 24 patients.

Conclusion:

The utility of FNAB in the diagnosis of lymphoma in the head and neck region is discussed. FNAB may not be sufficient unless immunofluorescence examination is also conducted. FNAB may lead to a considerable delay in establishing a definitive diagnosis. In the case of clinical suspicion, excisional biopsy is recommended without performing FNAB.

Keywords: Lymphoma, fine needle aspiration biopsy, excisional biopsy

References

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