ABSTRACT

No-rejlow phenomenon is the absence ofmyocardial perfusion despite adequate dilatation of the infarcı related coronary artery during percutaneous coronary interventıon. Uric acid (UA) release during ischemia and washout from the ischemic zone during reperfusion is adenine nucleotide breakdown product. Therefore uric acid may play reperfusion injury and no-rejlow. In this study, we aimed to compare serum uric acid value of ST segment e/evated Mİ patients groups whith norejlow phenomenon and normal miyocardial perfusion after primary coronary intervention.

47 patients was enrolled consecutively to this study. During hospital admission, patients blood sarnp/es were taken for serum uric acid value. Patients was grouped as no rejlow and normal perfusion groups according to myocardial blush grades (MBG). Patient with myocardial blush grades 0-1 were accepted as no-rejlow group, patients with MBG 2-3 normal peifusion group. When the serum uric acid value ofno-rejlow and normal peifusion groups was compared, there was statistificaly significant dif.ference ( respectively 6,680±1,11 versus 5,066±0,68 p<0,05) İn ST segment e/evated Ml patients with higher serum uric acid value bejare primary coronary intervention, no-rejlow phenomenon is developed more frequently. Uric acid may play important role in mechanism of no-rejlow phenomenon.