Schizencephaly and migration abnormality
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Case Report
P: 47-49
December 2005

Schizencephaly and migration abnormality

İstanbul Med J 2005;6(4):47-49
1. SSK İstanbul Hastanesi Nöroloji Kliniği
2. SSK İstanbul Eğitim Ve Araştırma Hastanesi Nöroloji Kliniği
3. Bakırköy Dr. Sadi Konuk Eğitim ve Araştırma Hastanesi, Nöroloji Kliniği, İstanbul, Türkiye
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ABSTRACT

Of disorders of brain development, neuronal migratian abnormalities are congenital malformatians caused by impairment of neuroblast migration in 3-5 th months of gestation.

An 18 year old male patient was examined twice because of the generalized tonic-clonic attack, with 1 year interval between these examinations, and in his computerized brain tomography and magnetic resonance screening analyses it was found that there were bilateral schizencephaly (closed lip) and poliymicrogria localized at postcentral and supramarginal gyrus.ln many syndromes, various migratian abnormalities are noted together with other systemic abnormalities.

We report this case, in the light of the literature, in whom there was major structural abnormality but no significant neurological deficit.

Keywords:
Neuronal migratian abnormality, schizencephaly, MR