ABSTRACT

Patients with restless le gs syndrome(llS) suffer from sensory and motor symptoms evoked in the limbs at rest. Symptoms increase in the evening and during the night. The circadien rhythm and the presence of involuntary periodic limb mavement in sleep (PLMS) which are frequently associated with arousals probably cause the leading symptom of sleep disturbances in US. Dopaminergic agents such as levodopa/dopa decarboxylase inhibitor (DDI) and dopamin agonists are considered the treatment of choice for llS and PLMS. The purpose ofthis case report is to overview the epidemiology, pathophysiology, elinical symptomatology and diagnosis of LLS and PLMS and to focus on the treatment strategies in both disorders.