ABSTRACT

Lymphomas comprise 3% to 5% of all malignancies, with non-Hodgkin’s lymphoma accounting for 60% of cases. The nasal cavities and paranasal sinuses are rarely affected by primary NHL. There are three subtypes of NHL on the basis of their immunohistochemical findings: B-cell lymphoma, T-cell lymphoma and natural killer (NK)/T-cell lymphoma. A 77 yearold woman presented at our clinic with a one month history of a nasal obstruction and unilateral epistaxis of the left nasal cavity. Punch biopsy reported a lymphoplasmocytic diffuse malignant infiltrate. Immunohistochemistry was strongly positive for the B cell associated markers CD20 and it was diagnosed as nasal septal B cell lymphoma.