Original Investigation

The Correlation between Cerebrovascular Disease and HBA1C Levels in Patients with Type 2 Diabetes Mellitus

10.5152/imj.2014.48615

  • Aysel Tekeşin
  • Belma Doğan
  • Orhan Yağız
  • Hayri Polat

İstanbul Med J 2014;15(1):40-42

Objective:

In this study, we aimed to investigate the relation of cerebrovascular disease with HbA1c levels in patients with type 2 diabetes mellitus.

Methods:

Tip 2 diabetic patients with iron deficiency anemia, high triglyceride levels, uremia, high bilirubin levels, chronic use of salicylates and opioids, and chronic alcohol abuse, which could have an impact on HbA1c levels, were excluded from the study. 60 diabetic patients with HbA1c levels measured routinely,whose initial diagnosis were ischemic stroke, were recruited to the study. 34 patients were female, while 26 were male. HbA1c levels were measured using high performance liquid chromatography.

Results:

Using our hospital laboratory reference ranges, in 63% of the patients HbA1c levels were found to be high.However, according to an another reference range in the literature the upper limit for normal levels was accepted as 1.5 times more than our limit. According to this literature, HbA1c levels were found to be high in 43% of patients. HbA1c levels were above 4,2-8% in 34 out of 60 patients, 8-12 % in 21 patients,and more than 12% in 5 patients.

Conclusion:

No correlation was found between glycemic control and development of cerebrovascular disease. We believe that further studies with larger patient groups should be conducted for more precise results.

Keywords: Cerebrovascular disease, HbA1c, diabetes mellitus