Objective:
We aimed to investigate the relationship between the neutrophil– lymphocyte ratio (NLR) and clinicopathological parameters during the diagnosis of follicular lymphoma (FL).
Methods:
The data of 21 patients who were diagnosed with FL between December 2011 and May 2015 were retrospectively analyzed. The median NLR was 2.01 (range, 0.46-4.59), and the cut-off score for NLR was determined to be 2. NLR was >2 in 11 (52%) patients.
Results:
No correlation was found between NLR and lactate dehydrogenase (LDH) levels; follicular lymphoma international prognostic index (FLIPI) score; disease stage; tumor grade; treatment necessity; presence of B symptoms; and presence of extranodal, bone marrow, hepatic, and splenic involvement (p>0.05).
Conclusion:
We could not demonstrate a relation between NLR and clinicopathological parameters in FL patients. The retrospective nature of the study, small sample size, short follow-up period, and indolent nature of FL may be the reasons for these unexpected results.
Keywords: Neutrophil lymphocyte ratio, follicular lymphoma, prognostic factor