Escherichia coli, the most important species in Ecsherichia genus within Enterobacteriaceae family, is responsible for human infections which urinary system infections but alsa gastroenteritis, peritonitis, cathater related infections, newbom menengitis, abcess, wound infections, biliary system infections and nasocomial infections.
In this study, we retrospectively evaluated antimicrobial susceptibility of E.coli strains that was isolated from outpatient and nasocomial infections and consequently resistance development in S.B.lstanbul Education and Research Hospital Microbiology Laboratory in 2004. We examined E.coli strains isolatedfrom urine, blood, cathater, bile, periton fluid, tracheal aspiration, wound samples about 586 outpatient and 81 nasocomial infections. W e found antimicrobial resistance percentages of nasocomial and outpatient strains like those:Ampiciline (% 76- 70), Ampiciline -Sulbactam and Amoxyciline-Clavunate (% 61-58), Trımetoprime- Sulphamethoksazole (% 54-46), Ciprojloxacin (% 48- 37), Gentamicin (% 33-20), Netilmicin ( % 20-11), Amikacin (% 6-2), Cefuroxim(% 38-37), Cefazolin (% 22-17), ceftazidim (% 17-8), Tazobactam-piperacilin (% 14-13), Ceftriaxone(%29-8), lmipenem (% 2- 0), Meropenem (% 2-0). Thatfor both groups resistance percentage of ciprojloxacin and trimetoprim-sulphametoxazole, which used first choice for ampırical treatment in urinary system infections, should catch attention of physicians.
Especially four nasocomial strains, resistance to lmipenem and Meropenem, are being considered that using of antimicrobials are required more attentive and infeciton control measures should be implemented more necessity.
Keywords: E.coli, antimicrobial susceptibility, 2004